Lung cancer is multifactorial because both genetic and environmental factors predispose to the condition. One of the well-documented ecological predisposing factors is tobacco smoking. There is a study that demonstrates the role of smoking-gene interactions in cancer etiology.
The study identified three single-nucleotide polymorphisms which are responsible for developing diseases. Among the three SNPs, one was for squamous cell carcinoma and the rest coded for non-small cell cancer of the lungs. The polymorphs offer potential biomarkers for screening and intervention of the risk of lung cancer through the examination of smoking behavior. The SNPs are useful for individual-based treatment plan prediction and prognosis.
The study aims at including other populations other than the Caucasians only. With the availability of more genotype data, the interactions between genes and smoking behavior would be more evident in the study on lung cancer.
Eric Lefkofsky is among the most influential tech figures in Chicago. He is well-known to donate large sums of money towards cancer studies. Eric also advocates for smarter approaches to curing cancer. Eric is behind a health-tech startup known as Tempus that tries to modernize the treatment of tumors. Tempus’ work is to collect and analyze genomic data using proprietary algorithms and statistical analysis tools. The purpose of data analysis is to provide the healthcare personnel with personalized and precise therapy. The firm uses state-of-the-art technology to sequence and analyze genomic data.
Born in 1969, Eric Lefkofsky schooled at the University of Chicago and achieved a Juris Doctor from the University of Michigan Law School. He is an American businessman who co-founded Tempus, Lightbank, ECHO, and Groupon. Lightbank is a venture fund that invests in disruptive technologies.
Together with his wife, Eric started Lefkofsky Foundation which is a charitable organization to support educational, scientific, and philanthropic trusts and causes globally. So far, the foundation has funded over 50 charitable organizations. The corporation focuses on children. Through the foundation, Eric advances high-impact initiatives that aim at improving the lives of underserved people in the communities.
The Lefkofsky family joined The Giving Pledge in 2013 where they donate a lot of cash to philanthropy. Eric is a trustee of Steppenwolf Theatre Company and Lurie Children’s Hospital. He teaches on entrepreneurship and how to build technology-based companies at the University of Chicago.
Eric Lefkofsky says that there are untapped molecular databases in healthcare hence he tries to develop applications that target the health field. He prides in reducing the cost of sequencing and analyzing genomes through his company, Tempus. He aims to personalize therapies for patients.